[et_pb_section fb_built=”1″ fullwidth=”on” disabled_on=”on|on|on” admin_label=”Secci\u00f3n” _builder_version=”4.16″ disabled=”on” global_colors_info=”{}”][et_pb_fullwidth_header title=”UNIDAD DE TOXICOLOG\u00cdA” text_orientation=”center” content_max_width=”none” admin_label=”T\u00edtulo de anchura completa” _builder_version=”4.16″ background_color=”#26aa9f” button_one_letter_spacing_hover=”0″ button_two_letter_spacing_hover=”0″ global_colors_info=”{}” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”on” button_one_letter_spacing__hover=”0″ button_two_letter_spacing__hover_enabled=”on” button_two_letter_spacing__hover=”0″ button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”on|on|on” admin_label=”section” _builder_version=”4.16″ disabled=”on” global_colors_info=”{}”][et_pb_row padding_mobile=”off” column_padding_mobile=”on” admin_label=”Fila” _builder_version=”4.16″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” max_width=”960px” make_fullwidth=”off” use_custom_width=”on” width_unit=”on” custom_width_px=”960px” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Texto” _builder_version=”4.16″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” use_border_color=”off” border_color=”#ffffff” border_style=”solid” global_colors_info=”{}”]<\/p>\n
La Unidad de Toxicolog\u00eda y Seguridad Qu\u00edmica del Instituto de BioIngenier\u00eda de la Universidad Miguel Hern\u00e1ndez est\u00e1 formada por los siguientes grupos de investigaci\u00f3n:<\/p>\n
[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row padding_mobile=”off” column_padding_mobile=”on” admin_label=”row” _builder_version=”4.16″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” max_width=”860px” make_fullwidth=”off” use_custom_width=”on” width_unit=”on” custom_width_px=”860px” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Texto” _builder_version=”4.16″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” use_border_color=”off” border_color=”#ffffff” border_style=”solid” global_colors_info=”{}”]<\/p>\n
El grupo est\u00e1 centrado en el estudio de mecanismos moleculares de toxicidad e identificaci\u00f3n de rutas de efecto adverso de diversos xenobi\u00f3ticos, desde nanopart\u00edculas hasta compuestos organofosforados como plaguicidas, retardadores de llama. El grupo tambi\u00e9n tiene una actividad en toxicolog\u00eda reguladora y en elaboraci\u00f3n de informes de evaluaci\u00f3n del riesgo de exposici\u00f3n a diversas sustancias qu\u00edmicas para la salud humana y el medio ambiente.<\/p>\n
[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row padding_mobile=”off” column_padding_mobile=”on” admin_label=”row” _builder_version=”4.16″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” max_width=”860px” make_fullwidth=”off” use_custom_width=”on” width_unit=”on” custom_width_px=”860px” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Texto” _builder_version=”4.16″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” use_border_color=”off” border_color=”#ffffff” border_style=”solid” global_colors_info=”{}”]<\/p>\n
El grupo de investigaci\u00f3n tiene como objetivo central el estudio de mecanismos de toxicidad y factores modificadores, tanto gen\u00e9ticos como ambientales, que afectan a la respuesta de las poblaciones expuestas a contaminantes ambientales, tales como compuestos org\u00e1nicos persistentes y alteradores endocrinos, f\u00e1rmacos y sustancias adictivas.<\/span><\/strong><\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ fullwidth=”on” disabled_on=”off|off|off” admin_label=”Secci\u00f3n” _builder_version=”4.16″ global_colors_info=”{}”][et_pb_fullwidth_header title=”TOXICOLOGY UNIT” text_orientation=”center” content_max_width=”none” admin_label=”T\u00edtulo de anchura completa” _builder_version=”4.16″ background_color=”#26aa9f” button_one_letter_spacing_hover=”0″ button_two_letter_spacing_hover=”0″ global_colors_info=”{}” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”on” button_one_letter_spacing__hover=”0″ button_two_letter_spacing__hover_enabled=”on” button_two_letter_spacing__hover=”0″ button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”] [\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”off|off|off” admin_label=”section” _builder_version=”4.16″ global_colors_info=”{}”][et_pb_row padding_mobile=”off” column_padding_mobile=”on” admin_label=”Fila” _builder_version=”4.16″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” make_fullwidth=”off” use_custom_width=”on” width_unit=”on” custom_width_px=”960px” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Texto” _builder_version=”4.16″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” use_border_color=”off” border_color=”#ffffff” border_style=”solid” global_colors_info=”{}”]<\/p>\n The Toxicology and Chemical Safety Unit of the Institute of Bioengineering of the Miguel Hern\u00e1ndez University is formed by the following research groups:<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row padding_mobile=”off” column_padding_mobile=”on” admin_label=”row” _builder_version=”4.16″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” make_fullwidth=”off” use_custom_width=”on” width_unit=”on” custom_width_px=”860px” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Texto” _builder_version=”4.16″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” use_border_color=”off” border_color=”#ffffff” border_style=”solid” global_colors_info=”{}”]<\/p>\n The group is focused on the study of molecular mechanisms of toxicity and identification of adverse effect pathways of various xenobiotics, from nanoparticles to organophosphorus compounds such as pesticides, flame retardants. The group is also active in regulatory toxicology and in the preparation of risk assessment reports on exposure to various chemicals for human health and the environment.<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row padding_mobile=”off” column_padding_mobile=”on” admin_label=”row” _builder_version=”4.16″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” make_fullwidth=”off” use_custom_width=”on” width_unit=”on” custom_width_px=”860px” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Texto” _builder_version=”4.16″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” use_border_color=”off” border_color=”#ffffff” border_style=”solid” global_colors_info=”{}”]<\/p>\n The main objective of the research group is to study the mechanisms of toxicity and modifying factors, both genetic and environmental, that affect the response of populations exposed to environmental pollutants, such as persistent organic compounds and endocrine disruptors, drugs and addictive substances.<\/span><\/strong><\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.17.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.17.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.17.4″ _module_preset=”default” global_colors_info=”{}” custom_padding=”10px|||||”]<\/p>\n In the Clinical Pharmacology group we investigate interindividual variability in drug response, especially in the area of pain and cognitive diversity. Our work focuses on the monitoring of adverse events and the use of pharmacogenetic markers to improve the benefit\/risk of drugs. To this end, we have specific lines of work on drugs abuse and dependence, as well as sleep disorders. The analysis of sex\/gender interaction is included as a cross-cutting theme in all of them.<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”on|on|on” _builder_version=”4.16″ disabled=”on” global_colors_info=”{}”][et_pb_row _builder_version=”4.16″ global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ global_colors_info=”{}”][:es _i=”0″ _address=”4.0.0.0″ \/][:en _i=”1″ _address=”4.0.0.1″ \/][: _i=”2″ _address=”4.0.0.2″ \/][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" GRUPOS La Unidad de Toxicolog\u00eda y Seguridad Qu\u00edmica del Instituto de BioIngenier\u00eda de la Universidad Miguel Hern\u00e1ndez est\u00e1 formada por los siguientes grupos de investigaci\u00f3n:Toxicolog\u00eda y Salud Medioambiental El grupo est\u00e1 centrado en el estudio de mecanismos moleculares de toxicidad e identificaci\u00f3n de rutas de efecto adverso de diversos xenobi\u00f3ticos, desde nanopart\u00edculas hasta compuestos organofosforados […]<\/p>\n","protected":false},"author":17014,"featured_media":0,"parent":0,"menu_order":73,"comment_status":"open","ping_status":"open","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_links_to":"","_links_to_target":""},"_links":{"self":[{"href":"https:\/\/bioingenieria.umh.es\/en\/wp-json\/wp\/v2\/pages\/4267"}],"collection":[{"href":"https:\/\/bioingenieria.umh.es\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/bioingenieria.umh.es\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/bioingenieria.umh.es\/en\/wp-json\/wp\/v2\/users\/17014"}],"replies":[{"embeddable":true,"href":"https:\/\/bioingenieria.umh.es\/en\/wp-json\/wp\/v2\/comments?post=4267"}],"version-history":[{"count":0,"href":"https:\/\/bioingenieria.umh.es\/en\/wp-json\/wp\/v2\/pages\/4267\/revisions"}],"wp:attachment":[{"href":"https:\/\/bioingenieria.umh.es\/en\/wp-json\/wp\/v2\/media?parent=4267"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}GROUPS<\/strong><\/h2>\n
Toxicology and Environmental Health<\/a><\/span><\/h2>\n
Toxicology and Population Risk<\/a><\/span><\/h2>\n
Clinical Pharmacology<\/a><\/span><\/h2>\n