{"id":4450,"date":"2021-04-16T09:55:30","date_gmt":"2021-04-16T09:55:30","guid":{"rendered":"https:\/\/bioingenieria.zeus.umh.es\/grupo-de-maria-rosa-ponce-molet\/"},"modified":"2022-04-13T11:20:11","modified_gmt":"2022-04-13T11:20:11","slug":"grupo-de-maria-rosa-ponce-molet","status":"publish","type":"page","link":"https:\/\/bioingenieria.umh.es\/en\/unidad-de-genetica\/grupo-de-maria-rosa-ponce-molet\/","title":{"rendered":"Grupo de Mar\u00eda Rosa Ponce Molet"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; fullwidth=&#8221;on&#8221; disabled_on=&#8221;on|on|on&#8221; admin_label=&#8221;Secci\u00f3n&#8221; _builder_version=&#8221;3.22&#8243; disabled=&#8221;on&#8221;][et_pb_fullwidth_header title=&#8221;Grupo de Mar\u00eda Rosa Ponce Molet&#8221; text_orientation=&#8221;center&#8221; content_max_width=&#8221;none&#8221; admin_label=&#8221;T\u00edtulo de anchura completa&#8221; _builder_version=&#8221;3.16&#8243; background_color=&#8221;#649922&#8243; button_one_letter_spacing_hover=&#8221;0&#8243; button_two_letter_spacing_hover=&#8221;0&#8243; button_one_text_size__hover_enabled=&#8221;off&#8221; button_two_text_size__hover_enabled=&#8221;off&#8221; button_one_text_color__hover_enabled=&#8221;off&#8221; button_two_text_color__hover_enabled=&#8221;off&#8221; button_one_border_width__hover_enabled=&#8221;off&#8221; button_two_border_width__hover_enabled=&#8221;off&#8221; button_one_border_color__hover_enabled=&#8221;off&#8221; button_two_border_color__hover_enabled=&#8221;off&#8221; button_one_border_radius__hover_enabled=&#8221;off&#8221; button_two_border_radius__hover_enabled=&#8221;off&#8221; button_one_letter_spacing__hover_enabled=&#8221;on&#8221; button_one_letter_spacing__hover=&#8221;0&#8243; button_two_letter_spacing__hover_enabled=&#8221;on&#8221; button_two_letter_spacing__hover=&#8221;0&#8243; button_one_bg_color__hover_enabled=&#8221;off&#8221; button_two_bg_color__hover_enabled=&#8221;off&#8221;][\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; disabled_on=&#8221;on|on|on&#8221; admin_label=&#8221;section&#8221; _builder_version=&#8221;3.22&#8243; disabled=&#8221;on&#8221;][et_pb_row padding_mobile=&#8221;off&#8221; column_padding_mobile=&#8221;on&#8221; admin_label=&#8221;row&#8221; _builder_version=&#8221;3.25&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; max_width=&#8221;980px&#8221; make_fullwidth=&#8221;off&#8221; use_custom_width=&#8221;on&#8221; width_unit=&#8221;on&#8221; custom_width_px=&#8221;980px&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_tabs admin_label=&#8221;Pesta\u00f1as&#8221; _builder_version=&#8221;3.0.87&#8243; tab_font=&#8221;Roboto||||&#8221; tab_line_height=&#8221;1.4em&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; use_border_color=&#8221;off&#8221; border_color=&#8221;#ffffff&#8221; border_style=&#8221;solid&#8221;][et_pb_tab title=&#8221;Informaci\u00f3n&#8221; _builder_version=&#8221;3.0.48&#8243; body_font=&#8221;||||&#8221; body_line_height=&#8221;2em&#8221; tab_font=&#8221;||||&#8221; tab_line_height=&#8221;2em&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; body_line_height_tablet=&#8221;2em&#8221; body_line_height_phone=&#8221;2em&#8221; tab_line_height_tablet=&#8221;2em&#8221; tab_line_height_phone=&#8221;2em&#8221;]<\/p>\n<table>\n<tbody>\n<tr>\n<td><strong>Responsable<\/strong><\/td>\n<td>Mar\u00eda Rosa Ponce Molet<\/td>\n<\/tr>\n<tr>\n<td><strong>Web propia<\/strong><\/td>\n<td><a href=\"http:\/\/genetics.edu.umh.es\/\" target=\"_blank\" rel=\"noopener\">http:\/\/genetics.edu.umh.es\/<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<h3>Resumen de la investigaci\u00f3n<\/h3>\n<p>&nbsp;<br \/>\nFALTA EL RESUMEN DEL GRUPO.<br \/>\n&nbsp;<\/p>\n<h3>L\u00edneas de investigaci\u00f3n<\/h3>\n<p>&nbsp;<\/p>\n<h3>L\u00ednea 1: An\u00e1lisis funcional de la ruta de los microARN en Arabidopis thaliana<\/h3>\n<p>Uno de los mecanismos de regulaci\u00f3n de la expresi\u00f3n de los genes eucari\u00f3ticos es el postranscripcional mediado por los ARN peque\u00f1os interferentes, que incluyen a los microARN (miARN). Para regular negativamente a sus dianas, estos peque\u00f1os ARN se incorporan a complejos de silenciamiento, en los que juega un papel central una prote\u00edna de la familia ARGONAUTE (AGO) tanto en los animales como en las plantas. En Arabidopsis, AGO1 es el principal componente de los complejos de silenciamiento mediados por miARN.&nbsp; El estudio de este tipo de regulaci\u00f3n tiene un gran potencial biotecnol\u00f3gico, ya que su manipulaci\u00f3n permite el silenciamiento selectivo de cualquier gen end\u00f3geno o viral. Mediante diversas aproximaciones gen\u00e9ticas y moleculares estamos estudiando las funciones e interacciones de AGO1 de Arabidopsis, y de otros componentes de la ruta de silenciamiento mediada por miARN.<br \/>\n&nbsp;<\/p>\n<h3>L\u00ednea 2:&nbsp;Control de la biog\u00e9nesis de los ribosomas en Arabidopsis<\/h3>\n<p>El ribosoma es una m\u00e1quina molecular muy conservada que se origin\u00f3 hace entre 3.000 y 4.000 millones de a\u00f1os, y cuya s\u00edntesis es el proceso que m\u00e1s energ\u00eda requiere en cualquier c\u00e9lula procariota o eucariota. Cataliza la traducci\u00f3n de los ARNm a prote\u00ednas en un proceso universal para todas las formas de vida. Las intrincadas v\u00edas que producen los ribosomas 80S del citoplasma demandan la mayor parte de la energ\u00eda y los recursos celulares de cualquier organismo, por lo que est\u00e1 sometido a estrictos controles gen\u00e9ticos para conseguir una estequiometr\u00eda adecuada de todos sus componentes, cuatro ARNr y unas 80 prote\u00ednas ribos\u00f3micas. La mayor parte de los conocimientos sobre la biog\u00e9nesis del ribosoma 80S citopl\u00e1smico proceden de estudios en Saccharomyces cerevisiae, el organismo eucariota en el que se ha abordado este proceso con mayor profundidad. De hecho, pr\u00e1cticamente todos los factores de biog\u00e9nesis del ribosoma (m\u00e1s de 250) han sido caracterizados funcionalmente en la levadura. Sin embargo, esta no es la situaci\u00f3n en otros organismos, incluidos los animales y las plantas, en los que la biog\u00e9nesis de los ribosomas ha sido menos estudiada. Nuestro principal objetivo es contribuir a esclarecer los mecanismos de control de la biog\u00e9nesis de los ribosomas en Arabidopsis, identificando los factores ribosomales que podr\u00edan controlar y coordinar la s\u00edntesis de los componentes del ribosoma.<\/p>\n<p>[\/et_pb_tab][et_pb_tab title=&#8221;Miembros&#8221; _builder_version=&#8221;3.0.48&#8243; body_font=&#8221;Roboto||||&#8221; body_line_height=&#8221;2em&#8221; tab_font=&#8221;Roboto||||&#8221; tab_line_height=&#8221;2em&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; body_line_height_tablet=&#8221;2em&#8221; body_line_height_phone=&#8221;2em&#8221; tab_line_height_tablet=&#8221;2em&#8221; tab_line_height_phone=&#8221;2em&#8221;]<\/p>\n<table>\n<tbody>\n<tr>\n<td style=\"text-align: left\" width=\"224\"><strong>Nombre<\/strong><\/td>\n<td style=\"text-align: left\" width=\"328\"><strong>Puesto<\/strong><\/td>\n<td style=\"text-align: left\" width=\"200\"><strong>Correo<\/strong><\/td>\n<td style=\"text-align: left\" width=\"200\"><strong>ORCID<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"font-weight: 400\">Mar\u00eda Rosa Ponce Molet<\/td>\n<td style=\"font-weight: 400\">Catedr\u00e1tica de Universidad<\/td>\n<td style=\"font-weight: 400\"><a href=\"mailto:mrponce@umh.es\">mrponce@umh.es<\/a><\/td>\n<td style=\"font-weight: 400\">0000-0003-0770-4230<\/td>\n<\/tr>\n<tr>\n<td style=\"font-weight: 400\">Raquel Sarmiento Ma\u00f1\u00fas<\/td>\n<td style=\"font-weight: 400\">Profesora Ayudante Doctora<\/td>\n<td style=\"font-weight: 400\"><a href=\"mailto:rsarmiento@umh.es\">rsarmiento@umh.es<\/a><\/td>\n<td style=\"font-weight: 400\">0000-0001-6929-8034<\/td>\n<\/tr>\n<tr>\n<td style=\"font-weight: 400\">Rosa Micol Ponce<\/td>\n<td style=\"font-weight: 400\">Contratada Postdoctoral<\/td>\n<td style=\"font-weight: 400\"><a href=\"mailto:rmicol@umh.es\">rmicol@umh.es<\/a><\/td>\n<td style=\"font-weight: 400\">0000-0001-9389-2906<\/td>\n<\/tr>\n<tr>\n<td style=\"font-weight: 400\">Adri\u00e1n Cabezas Fuster<\/td>\n<td style=\"font-weight: 400\">Contratado Postdoctoral<\/td>\n<td style=\"font-weight: 400\"><a href=\"mailto:acabezas@umh.es\">acabezas@umh.es<\/a><\/td>\n<td style=\"font-weight: 400\">0000-0001-5571-0665<\/td>\n<\/tr>\n<tr>\n<td style=\"font-weight: 400\">Sara Fontcuberta Cervera<\/td>\n<td style=\"font-weight: 400\">Contratada Postdoctoral<\/td>\n<td style=\"font-weight: 400\"><a href=\"mailto:sfontcuberta@umh.es\">sfontcuberta@umh.es<\/a><\/td>\n<td style=\"font-weight: 400\">0000-0001-9410-6946<\/td>\n<\/tr>\n<tr>\n<td style=\"font-weight: 400\">Diana Navarro Mart\u00ednez<\/td>\n<td style=\"font-weight: 400\">T\u00e9cnica de Apoyo a la Investigaci\u00f3n<\/td>\n<td style=\"font-weight: 400\"><a href=\"mailto:d.navarro@umh.es\" target=\"_blank\" rel=\"noopener\">d.navarro@umh.es<\/a><\/td>\n<td style=\"font-weight: 400\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>[\/et_pb_tab][et_pb_tab title=&#8221;Publicaciones&#8221; _builder_version=&#8221;3.0.48&#8243; body_font=&#8221;Roboto||||&#8221; body_line_height=&#8221;2em&#8221; tab_font=&#8221;Roboto||||&#8221; tab_line_height=&#8221;2em&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; body_line_height_tablet=&#8221;2em&#8221; body_line_height_phone=&#8221;2em&#8221; tab_line_height_tablet=&#8221;2em&#8221; tab_line_height_phone=&#8221;2em&#8221;]<\/p>\n<p style=\"font-weight: 400\">M.R. Ponce, J. L. Micol, R. Sarmiento-Ma\u00f1\u00fas, S. Fontcuberta-Cervera, A. Cabezas-Fuster, A. de Bures , J. S\u00e1ez-V\u00e1squez<br \/>\n<strong><a href=\"http:\/\/www.plantphysiol.org\/content\/184\/4\/2022\" target=\"_blank\" rel=\"noopener\">SMALL ORGAN4 Is a Ribosome Biogenesis Factor Involved in 5.8S Ribosomal RNA Maturation<\/a><\/strong><br \/>\nPlant Physiology 184, 2022-2039 (2020). <a href=\"http:\/\/www.plantphysiol.org\/content\/plantphysiol\/184\/4\/2022.full.pdf\" target=\"_blank\" rel=\"noopener\">PDF<\/a><\/p>\n<p style=\"font-weight: 400\">U. Aceituno-Valenzuela, R. Micol-Ponce, M.R. Ponce<br \/>\n<strong><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32303790\/\" target=\"_blank\" rel=\"noopener\">Genome-wide analysis of CCHC-type zinc finger (ZCCHC) proteins in yeast, Arabidopsis, and humans<\/a><\/strong><br \/>\nCellular and Molecular Life Sciences 77, 3991-4014 (2020).<\/p>\n<p style=\"font-weight: 400\">M.R. Ponce, J.L. Micol<br \/>\n<strong><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32077508\/\" target=\"_blank\" rel=\"noopener\">A cornucopia of mutants for understanding plant embryo development<\/a><\/strong><br \/>\nNew Phytologist 226, 289-291&nbsp;(2020).<\/p>\n<p style=\"font-weight: 400\">D. Wilson-S\u00e1nchez, S.D. Lup, R. Sarmiento-Ma\u00f1\u00fas, M.R. Ponce, J.L. Micol<br \/>\n<strong><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31544937\/\" target=\"_blank\" rel=\"noopener\">Next-generation forward genetic screens: using simulated data to improve the design of mapping-by-sequencing experiments in Arabidopsis<\/a><\/strong><br \/>\nNucleic Acids Research 47, e140&nbsp;(2019).<\/p>\n<p style=\"font-weight: 400\">R. Micol-Ponce, R. Sarmiento-Ma\u00f1\u00fas, A. Ruiz-Bay\u00f3n, C. Montaci\u00e9, J. S\u00e1ez-Vasquez, M.R. Ponce<br \/>\n<strong><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30361235\/\" target=\"_blank\" rel=\"noopener\">Arabidopsis RIBOSOMAL RNA PROCESSING 7 is required for 18S rRNA maturation. Plant Cell 30, 2855-2872<\/a><\/strong><br \/>\nThe Plant Cell: In a Nutshell&nbsp;(2018).<\/p>\n<p>[\/et_pb_tab][et_pb_tab title=&#8221;Proyectos&#8221; _builder_version=&#8221;3.0.48&#8243; body_font=&#8221;||||&#8221; body_line_height=&#8221;2em&#8221; tab_font=&#8221;||||&#8221; tab_line_height=&#8221;2em&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; body_line_height_tablet=&#8221;2em&#8221; body_line_height_phone=&#8221;2em&#8221; tab_line_height_tablet=&#8221;2em&#8221; tab_line_height_phone=&#8221;2em&#8221;]<\/p>\n<p style=\"font-weight: 400\">Ayudas para el fomento del empleo joven y la implantaci\u00f3n de la Garant\u00eda Juvenil en I+D+i. Agencia financiadora: MCIU AEI PEJ2018-001974-A. Vigencia: 2019-2021.<\/p>\n<p><em>PI: Mar\u00eda Rosa Ponce<\/em><\/p>\n<hr>\n<p style=\"font-weight: 400\">Relaci\u00f3n entre la maquinaria del microARN y la traducci\u00f3n del ARNm. Agencia de financiaci\u00f3n: MinEICo BIO2017-89728-R. Vigencia: 2018-2020.<\/p>\n<p><em>PI: Mar\u00eda Rosa Ponce<\/em><\/p>\n<hr>\n<p style=\"font-weight: 400\">Plataforma rob\u00f3tica para la fen\u00f3mica de las plantas. Agencia financiadora: Generalitat Valenciana IDIFEDER\/2020\/019. Vigencia: 2020.<\/p>\n<p><em>PI: Jos\u00e9 Luis Micol<\/em><\/p>\n<hr>\n<p style=\"font-weight: 400\">Claves moleculares del crecimiento de las plantas: un enfoque multidisciplinar. Agencia financiadora: Generalitat Valenciana PROMETEO\/2019\/117. Vigencia: 2019-2022.<\/p>\n<p><em>PI: Jos\u00e9 Luis Micol<\/em><\/p>\n<hr>\n<p style=\"font-weight: 400\">Unidad de fen\u00f3mica vegetal. Agencia de financiaci\u00f3n: MCIU EQC2019-006592-P. Vigencia: 2019-2021.<\/p>\n<p><em>PI: Jos\u00e9 Luis Micol<\/em><\/p>\n<p>[\/et_pb_tab][et_pb_tab title=&#8221;Actividades&#8221; _builder_version=&#8221;3.0.48&#8243; body_font=&#8221;||||&#8221; body_line_height=&#8221;2em&#8221; tab_font=&#8221;||||&#8221; tab_line_height=&#8221;2em&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; body_line_height_tablet=&#8221;2em&#8221; body_line_height_phone=&#8221;2em&#8221; tab_line_height_tablet=&#8221;2em&#8221; tab_line_height_phone=&#8221;2em&#8221;][\/et_pb_tab][\/et_pb_tabs][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; fullwidth=&#8221;on&#8221; disabled_on=&#8221;off|off|off&#8221; admin_label=&#8221;Secci\u00f3n&#8221; _builder_version=&#8221;3.22&#8243;][et_pb_fullwidth_header title=&#8221;Mar\u00eda Rosa Ponce Molet Group&#8221; text_orientation=&#8221;center&#8221; content_max_width=&#8221;none&#8221; admin_label=&#8221;T\u00edtulo de anchura completa&#8221; _builder_version=&#8221;3.16&#8243; background_color=&#8221;#649922&#8243; button_one_letter_spacing_hover=&#8221;0&#8243; button_two_letter_spacing_hover=&#8221;0&#8243; button_one_text_size__hover_enabled=&#8221;off&#8221; button_two_text_size__hover_enabled=&#8221;off&#8221; button_one_text_color__hover_enabled=&#8221;off&#8221; button_two_text_color__hover_enabled=&#8221;off&#8221; button_one_border_width__hover_enabled=&#8221;off&#8221; button_two_border_width__hover_enabled=&#8221;off&#8221; button_one_border_color__hover_enabled=&#8221;off&#8221; button_two_border_color__hover_enabled=&#8221;off&#8221; button_one_border_radius__hover_enabled=&#8221;off&#8221; button_two_border_radius__hover_enabled=&#8221;off&#8221; button_one_letter_spacing__hover_enabled=&#8221;on&#8221; button_one_letter_spacing__hover=&#8221;0&#8243; button_two_letter_spacing__hover_enabled=&#8221;on&#8221; button_two_letter_spacing__hover=&#8221;0&#8243; button_one_bg_color__hover_enabled=&#8221;off&#8221; button_two_bg_color__hover_enabled=&#8221;off&#8221;][\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; disabled_on=&#8221;off|off|off&#8221; admin_label=&#8221;section&#8221; _builder_version=&#8221;3.22&#8243;][et_pb_row padding_mobile=&#8221;off&#8221; column_padding_mobile=&#8221;on&#8221; admin_label=&#8221;row&#8221; _builder_version=&#8221;3.25&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; max_width=&#8221;980px&#8221; make_fullwidth=&#8221;off&#8221; use_custom_width=&#8221;on&#8221; width_unit=&#8221;on&#8221; custom_width_px=&#8221;980px&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_tabs admin_label=&#8221;Pesta\u00f1as&#8221; _builder_version=&#8221;4.2.2&#8243; tab_font=&#8221;Roboto||||&#8221; tab_line_height=&#8221;1.4em&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; use_border_color=&#8221;off&#8221; border_color=&#8221;#ffffff&#8221; border_style=&#8221;solid&#8221;][et_pb_tab title=&#8221;Information&#8221; _builder_version=&#8221;4.2.2&#8243; body_font=&#8221;||||&#8221; body_line_height=&#8221;2em&#8221; tab_font=&#8221;||||&#8221; tab_line_height=&#8221;2em&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; body_line_height_tablet=&#8221;2em&#8221; body_line_height_phone=&#8221;2em&#8221; tab_line_height_tablet=&#8221;2em&#8221; tab_line_height_phone=&#8221;2em&#8221;]<\/p>\n<table>\n<tbody>\n<tr>\n<td><strong>Responsible<\/strong><\/td>\n<td>Mar\u00eda Rosa Ponce Molet<\/td>\n<\/tr>\n<tr>\n<td><strong>Website<\/strong><\/td>\n<td><a href=\"http:\/\/genetics.edu.umh.es\/\" target=\"_blank\" rel=\"noopener\">http:\/\/genetics.edu.umh.es\/<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<h3>Research summary<\/h3>\n<p>THE GROUP&#8217;S SUMMARY IS MISSING.\u00a0<\/p>\n<h3>Research lines<\/h3>\n<p>&nbsp;<\/p>\n<h3 style=\"text-align: justify\">Line\u00a01: Functional analysis of the microRNA pathway in Arabidopis thaliana<\/h3>\n<p style=\"text-align: justify\">One of the mechanisms of eukaryotic gene expression regulation is post-transcriptional, mediated by small interfering RNAs, which include microRNAs (miRNAs). To negatively regulate their targets, these small RNAs are incorporated into silencing complexes, in which a protein of the ARGONAUTE (AGO) family plays a central role in both animals and plants. In Arabidopsis, AGO1 is the main component of miRNA-mediated silencing complexes.\u00a0 The study of this type of regulation has great biotechnological potential, since its manipulation allows the selective silencing of any endogenous or viral gene. We are studying the functions and interactions of Arabidopsis AGO1 and other components of the miRNA-mediated silencing pathway by means of different genetic and molecular approaches.\u00a0<\/p>\n<h3 style=\"text-align: justify\">Line 2:\u00a0Control of ribosome biogenesis in Arabidopsis<\/h3>\n<p style=\"text-align: justify\">The ribosome is a high conserved molecular machine that originated 3 to 4 billion years ago, and whose synthesis is the most energy-demanding process in any prokaryotic or eukaryotic cell. It catalyzes the translation of mRNAs into proteins in a process universal to all life forms. The intricate pathways that produce 80S cytoplasmic ribosomes demand most of cell energy and resources in any organism, so it is under strict genetic controls to get a proper stoichiometry of all its components, four rRNAs and about 80 ribosomal proteins. Most of knowledge about the biogenesis of the cytoplasmic 80S ribosome comes from studies in Saccharomyces cerevisiae, the eukaryotic organism in which this process has been addressed in greater depth. In fact, virtually all of ribosome biogenesis factors (more than 250) have been functionally characterized in yeast. However, this is not the situation in other organisms, including animals and plants where ribosome biogenesis has been more poorly studied. Our main goal is to contribute to clarify the mechanisms of control of ribosome biogenesis in Arabidopsis, identifying ribosomal factors that could control and coordinate the synthesis of the components of the ribosome.<\/p>\n<p>[\/et_pb_tab][et_pb_tab title=&#8221;Members&#8221; _builder_version=&#8221;3.0.48&#8243; body_font=&#8221;Roboto||||&#8221; body_line_height=&#8221;2em&#8221; tab_font=&#8221;Roboto||||&#8221; tab_line_height=&#8221;2em&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; body_line_height_tablet=&#8221;2em&#8221; body_line_height_phone=&#8221;2em&#8221; tab_line_height_tablet=&#8221;2em&#8221; tab_line_height_phone=&#8221;2em&#8221;]<\/p>\n<table>\n<tbody>\n<tr>\n<td style=\"text-align: left\" width=\"224\"><strong>Name<\/strong><\/td>\n<td style=\"text-align: left\" width=\"328\"><strong>Position<\/strong><\/td>\n<td style=\"text-align: left\" width=\"200\"><strong>e-mail<\/strong><\/td>\n<td style=\"text-align: left\" width=\"200\"><strong>ORCID<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"font-weight: 400\">Mar\u00eda Rosa Ponce Molet<\/td>\n<td style=\"font-weight: 400\">Full Professor<\/td>\n<td style=\"font-weight: 400\"><a href=\"mailto:mrponce@umh.es\">mrponce@umh.es<\/a><\/td>\n<td style=\"font-weight: 400\">0000-0003-0770-4230<\/td>\n<\/tr>\n<tr>\n<td style=\"font-weight: 400\">Raquel Sarmiento Ma\u00f1\u00fas<\/td>\n<td style=\"font-weight: 400\">Assistant Professor<\/td>\n<td style=\"font-weight: 400\"><a href=\"mailto:rsarmiento@umh.es\">rsarmiento@umh.es<\/a><\/td>\n<td style=\"font-weight: 400\">0000-0001-6929-8034<\/td>\n<\/tr>\n<tr>\n<td style=\"font-weight: 400\">Rosa Micol Ponce<\/td>\n<td style=\"font-weight: 400\">Postdoctoral Contract<\/td>\n<td style=\"font-weight: 400\"><a href=\"mailto:rmicol@umh.es\">rmicol@umh.es<\/a><\/td>\n<td style=\"font-weight: 400\">0000-0001-9389-2906<\/td>\n<\/tr>\n<tr>\n<td style=\"font-weight: 400\">Adri\u00e1n Cabezas Fuster<\/td>\n<td style=\"font-weight: 400\">Postdoctoral Contract<\/td>\n<td style=\"font-weight: 400\"><a href=\"mailto:acabezas@umh.es\">acabezas@umh.es<\/a><\/td>\n<td style=\"font-weight: 400\">0000-0001-5571-0665<\/td>\n<\/tr>\n<tr>\n<td style=\"font-weight: 400\">Sara Fontcuberta Cervera<\/td>\n<td style=\"font-weight: 400\">Postdoctoral Contract<\/td>\n<td style=\"font-weight: 400\"><a href=\"mailto:sfontcuberta@umh.es\">sfontcuberta@umh.es<\/a><\/td>\n<td style=\"font-weight: 400\">0000-0001-9410-6946<\/td>\n<\/tr>\n<tr>\n<td style=\"font-weight: 400\">Diana Navarro Mart\u00ednez<\/td>\n<td style=\"font-weight: 400\">Research Support Technician<\/td>\n<td style=\"font-weight: 400\"><a href=\"mailto:d.navarro@umh.es\" target=\"_blank\" rel=\"noopener\">d.navarro@umh.es<\/a><\/td>\n<td style=\"font-weight: 400\">\u00a0<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>[\/et_pb_tab][et_pb_tab title=&#8221;Publications&#8221; _builder_version=&#8221;3.0.48&#8243; body_font=&#8221;Roboto||||&#8221; body_line_height=&#8221;2em&#8221; tab_font=&#8221;Roboto||||&#8221; tab_line_height=&#8221;2em&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; body_line_height_tablet=&#8221;2em&#8221; body_line_height_phone=&#8221;2em&#8221; tab_line_height_tablet=&#8221;2em&#8221; tab_line_height_phone=&#8221;2em&#8221;]<\/p>\n<p style=\"font-weight: 400\">M.R. Ponce, J. L. Micol, R. Sarmiento-Ma\u00f1\u00fas, S. Fontcuberta-Cervera, A. Cabezas-Fuster, A. de Bures , J. S\u00e1ez-V\u00e1squez<br \/>\n<strong><a href=\"http:\/\/www.plantphysiol.org\/content\/184\/4\/2022\" target=\"_blank\" rel=\"noopener\">SMALL ORGAN4 Is a Ribosome Biogenesis Factor Involved in 5.8S Ribosomal RNA Maturation<\/a><\/strong><br \/>\nPlant Physiology 184, 2022-2039 (2020). <a href=\"http:\/\/www.plantphysiol.org\/content\/plantphysiol\/184\/4\/2022.full.pdf\" target=\"_blank\" rel=\"noopener\">PDF<\/a><\/p>\n<p style=\"font-weight: 400\">U. Aceituno-Valenzuela, R. Micol-Ponce, M.R. Ponce<br \/>\n<strong><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32303790\/\" target=\"_blank\" rel=\"noopener\">Genome-wide analysis of CCHC-type zinc finger (ZCCHC) proteins in yeast, Arabidopsis, and humans<\/a><\/strong><br \/>\nCellular and Molecular Life Sciences 77, 3991-4014 (2020).<\/p>\n<p style=\"font-weight: 400\">M.R. Ponce, J.L. Micol<br \/>\n<strong><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32077508\/\" target=\"_blank\" rel=\"noopener\">A cornucopia of mutants for understanding plant embryo development<\/a><\/strong><br \/>\nNew Phytologist 226, 289-291&nbsp;(2020).<\/p>\n<p style=\"font-weight: 400\">D. Wilson-S\u00e1nchez, S.D. Lup, R. Sarmiento-Ma\u00f1\u00fas, M.R. Ponce, J.L. Micol<br \/>\n<strong><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31544937\/\" target=\"_blank\" rel=\"noopener\">Next-generation forward genetic screens: using simulated data to improve the design of mapping-by-sequencing experiments in Arabidopsis<\/a><\/strong><br \/>\nNucleic Acids Research 47, e140&nbsp;(2019).<\/p>\n<p style=\"font-weight: 400\">R. Micol-Ponce, R. Sarmiento-Ma\u00f1\u00fas, A. Ruiz-Bay\u00f3n, C. Montaci\u00e9, J. S\u00e1ez-Vasquez, M.R. Ponce<br \/>\n<strong><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30361235\/\" target=\"_blank\" rel=\"noopener\">Arabidopsis RIBOSOMAL RNA PROCESSING 7 is required for 18S rRNA maturation. Plant Cell 30, 2855-2872<\/a><\/strong><br \/>\nThe Plant Cell: In a Nutshell&nbsp;(2018).<\/p>\n<p>[\/et_pb_tab][et_pb_tab title=&#8221;Projects&#8221; _builder_version=&#8221;4.2.2&#8243; body_font=&#8221;||||&#8221; body_line_height=&#8221;2em&#8221; tab_font=&#8221;||||&#8221; tab_line_height=&#8221;2em&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; body_line_height_tablet=&#8221;2em&#8221; body_line_height_phone=&#8221;2em&#8221; tab_line_height_tablet=&#8221;2em&#8221; tab_line_height_phone=&#8221;2em&#8221;]<\/p>\n<p style=\"font-weight: 400;text-align: justify\">Aid for the promotion of young employment and implementation of the Youth Guarantee in R+D+i. Funding agency: MCIU AEI PEJ2018-001974-A. Duration: 2019-2021.<br \/><em>PI: Mar\u00eda Rosa Ponce<\/em><\/p>\n<hr \/>\n<p style=\"font-weight: 400;text-align: justify\">Relationship between the microRNA machinery and mRNA translation. Funding agency: MinEICo BIO2017-89728-R. Duration: 2018-2020.<br \/><em>PI: Mar\u00eda Rosa Ponce<\/em><\/p>\n<hr \/>\n<p style=\"font-weight: 400;text-align: justify\">Robotic platform for plant phenomics. Funding agency: Generalitat Valenciana IDIFEDER\/2020\/019. Duration: 2020.<br \/><em>PI: Jos\u00e9 Luis Micol<\/em><\/p>\n<hr \/>\n<p style=\"font-weight: 400;text-align: justify\">Molecular keys to plant growth: a multidisciplinary approach. Funding agency: Generalitat Valenciana PROMETEO\/2019\/117. Duration: 2019-2022.<br \/><em>PI: Jos\u00e9 Luis Micol<\/em><\/p>\n<hr \/>\n<p style=\"font-weight: 400;text-align: justify\">Plant phenomics unit. Funding agency: MCIU EQC2019-006592-P. Duration: 2019-2021.<br \/><em>PI: Jos\u00e9 Luis Micol<\/em><\/p>\n<p>[\/et_pb_tab][et_pb_tab title=&#8221;Activities&#8221; _builder_version=&#8221;3.0.48&#8243; body_font=&#8221;||||&#8221; body_line_height=&#8221;2em&#8221; tab_font=&#8221;||||&#8221; tab_line_height=&#8221;2em&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; body_line_height_tablet=&#8221;2em&#8221; body_line_height_phone=&#8221;2em&#8221; tab_line_height_tablet=&#8221;2em&#8221; tab_line_height_phone=&#8221;2em&#8221;][\/et_pb_tab][\/et_pb_tabs][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; disabled_on=&#8221;on|on|on&#8221; _builder_version=&#8221;4.2.2&#8243; disabled=&#8221;on&#8221;][et_pb_row _builder_version=&#8221;4.2.2&#8243;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.2.2&#8243;][:es _i=&#8221;0&#8243; _address=&#8221;4.0.0.0&#8243; \/][:en _i=&#8221;1&#8243; _address=&#8221;4.0.0.1&#8243; \/][: _i=&#8221;2&#8243; _address=&#8221;4.0.0.2&#8243; \/][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Responsable Mar\u00eda Rosa Ponce Molet Web propia http:\/\/genetics.edu.umh.es\/ &nbsp; Resumen de la investigaci\u00f3n &nbsp; FALTA EL RESUMEN DEL GRUPO. &nbsp; L\u00edneas de investigaci\u00f3n &nbsp; L\u00ednea 1: An\u00e1lisis funcional de la ruta de los microARN en Arabidopis thaliana Uno de los mecanismos de regulaci\u00f3n de la expresi\u00f3n de los genes eucari\u00f3ticos es el postranscripcional mediado por [&hellip;]<\/p>\n","protected":false},"author":17017,"featured_media":0,"parent":4240,"menu_order":39,"comment_status":"open","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_links_to":"","_links_to_target":""},"_links":{"self":[{"href":"https:\/\/bioingenieria.umh.es\/en\/wp-json\/wp\/v2\/pages\/4450"}],"collection":[{"href":"https:\/\/bioingenieria.umh.es\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/bioingenieria.umh.es\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/bioingenieria.umh.es\/en\/wp-json\/wp\/v2\/users\/17017"}],"replies":[{"embeddable":true,"href":"https:\/\/bioingenieria.umh.es\/en\/wp-json\/wp\/v2\/comments?post=4450"}],"version-history":[{"count":0,"href":"https:\/\/bioingenieria.umh.es\/en\/wp-json\/wp\/v2\/pages\/4450\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/bioingenieria.umh.es\/en\/wp-json\/wp\/v2\/pages\/4240"}],"wp:attachment":[{"href":"https:\/\/bioingenieria.umh.es\/en\/wp-json\/wp\/v2\/media?parent=4450"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}