{"id":4462,"date":"2021-12-21T13:18:06","date_gmt":"2021-12-21T13:18:06","guid":{"rendered":"https:\/\/bioingenieria.zeus.umh.es\/grupo-de-victor-quesada-y-pedro-robles\/"},"modified":"2022-02-09T11:08:17","modified_gmt":"2022-02-09T11:08:17","slug":"grupo-de-victor-quesada-y-pedro-robles","status":"publish","type":"page","link":"https:\/\/bioingenieria.umh.es\/en\/unidad-de-genetica\/grupo-de-victor-quesada-y-pedro-robles\/","title":{"rendered":"Grupo de V\u00edctor Quesada y Pedro Robles"},"content":{"rendered":"

[et_pb_section fb_built=”1″ fullwidth=”on” disabled_on=”on|on|on” admin_label=”Secci\u00f3n” _builder_version=”3.22″ disabled=”on”][et_pb_fullwidth_header title=”Grupo de V\u00edctor Quesada y Pedro Robles” text_orientation=”center” content_max_width=”none” admin_label=”T\u00edtulo de anchura completa” _builder_version=”3.16″ background_color=”#649922″ button_one_letter_spacing_hover=”0″ button_two_letter_spacing_hover=”0″ button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”on” button_one_letter_spacing__hover=”0″ button_two_letter_spacing__hover_enabled=”on” button_two_letter_spacing__hover=”0″ button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”on|on|on” admin_label=”section” _builder_version=”3.22″ disabled=”on”][et_pb_row padding_mobile=”off” column_padding_mobile=”on” admin_label=”row” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” max_width=”980px” make_fullwidth=”off” use_custom_width=”on” width_unit=”on” custom_width_px=”980px”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_tabs admin_label=”Pesta\u00f1as” _builder_version=”4.2.2″ tab_font=”Roboto||||” tab_line_height=”1.4em” background_size=”initial” background_position=”top_left” background_repeat=”repeat” use_border_color=”off” border_color=”#ffffff” border_style=”solid”][et_pb_tab title=”Informaci\u00f3n” _builder_version=”4.2.2″ body_font=”||||” body_line_height=”2em” tab_font=”||||” tab_line_height=”2em” background_size=”initial” background_position=”top_left” background_repeat=”repeat” body_line_height_tablet=”2em” body_line_height_phone=”2em” tab_line_height_tablet=”2em” tab_line_height_phone=”2em”]<\/p>\n\n\n\n
Responsable<\/strong><\/td>\nV\u00edctor Quesada y Pedro Robles<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

RESUMEN DE LA INVESTIGACI\u00d3N<\/strong><\/h4>\n

En nuestros laboratorios se lleva a cabo una aproximaci\u00f3n de gen\u00e9tica inversa con el fin de identificar y caracterizar en <\/span>Arabidopsis thaliana<\/span><\/i>, mutantes afectados en genes nucleares que codifican prote\u00ednas implicadas en el flujo de la informaci\u00f3n gen\u00e9tica en los cloroplastos y las mitocondrias. Para la mayor\u00eda de los genes objeto de estudio no se hab\u00eda descrito previamente ning\u00fan fenotipo mutante a partir de la perturbaci\u00f3n de su funci\u00f3n. Nos hemos centrado en dos familias de prote\u00ednas: los factores de terminaci\u00f3n de la transcripci\u00f3n mitocondrial (mTERF) y las prote\u00ednas ribos\u00f3micas cloropl\u00e1sticas (PRC) o mitocondriales (PRM). Pretendemos avanzar en la comprensi\u00f3n de las funciones que los mTERF, las PRC y PRM desempa\u00f1an en el desarrollo, el crecimiento vegetal y en la adaptaci\u00f3n de las plantas al estr\u00e9s abi\u00f3tico, especialmente a la salinidad.<\/span><\/strong><\/p>\n

L\u00cdNEAS DE INVESTIGACI\u00d3N<\/strong><\/h4>\n

 <\/p>\n

L\u00ednea 1: Caracterizaci\u00f3n gen\u00e9tica y molecular de la familia de los factores de terminaci\u00f3n de la transcripci\u00f3n mitocondrial (mTERF) de Arabidopsis thaliana<\/i><\/strong><\/h4>\n

Los factores mTERF est\u00e1n codificados por genes nucleares y en las plantas llevan a cabo su funci\u00f3n en los cloroplastos y\/o las mitocondrias, donde se requieren para la correcta expresi\u00f3n de los genomas de estos org\u00e1nulos. Son muy pocos los genes mTERF de las plantas que se han caracterizado a partir del an\u00e1lisis de mutantes afectados en los mismos, a pesar de que su n\u00famero es considerablemente mayor que en los animales. En nuestros laboratorios estamos llevando a cabo la caracterizaci\u00f3n gen\u00e9tica, fenot\u00edpica y molecular de varios mutantes <\/span>mterf<\/span><\/i> de Arabidopsis (p.e. <\/span>mda1\/mterf5<\/span><\/i>, <\/span>mterf6<\/span><\/i> y <\/span>mterf9<\/span><\/i>) que presentan alteraciones en su crecimiento y desarrollo vegetativo, as\u00ed como una respuesta alterada al estr\u00e9s abi\u00f3tico.<\/span><\/strong><\/p>\n

\"l\u00ednea<\/p>\n

Los mutantes mtef6 son m\u00e1s sensibles al estr\u00e9s salino (150 mM NaCl) que la estirpe silvestre Columbia-0 (Col-0), durante la germinaci\u00f3n y el establecimiento de la pl\u00e1ntula. Adem\u00e1s, el mutante mterf6-5 muestra alteraciones durante el crecimiento y el desarrollo vegetativo y reproductivo.<\/em><\/p>\n

 <\/p>\n

L\u00ednea 2: An\u00e1lisis funcional de prote\u00ednas ribos\u00f3micas del cloroplasto y la mitocondria en\u00a0Arabidopsis thaliana<\/i><\/strong><\/h4>\n

Los ribosomas, integrados por ARN y prote\u00ednas, constituyen la maquinaria que traduce los ARN mensajeros en los procariotas as\u00ed como en el citoplasma, los cloroplastos y las mitocondrias de las c\u00e9lulas eucariotas. Con el objetivo de aumentar la comprensi\u00f3n de las funciones de las prote\u00ednas ribos\u00f3micas cloropl\u00e1sticas (PRC) o mitocondriales (PRM) en las plantas, hemos iniciado una aproximaci\u00f3n de gen\u00e9tica inversa para identificar y caracterizar en la planta modelo <\/span>Arabidopsis thaliana<\/span><\/i> mutantes afectados en este tipo de prote\u00ednas. Hemos identificado alelos portadores de una inserci\u00f3n de ADN-T en genes nucleares que cifran PRM o PRC y para los que no se han descrito alelos viables de p\u00e9rdida de funci\u00f3n. Actualmente estamos caracterizando estos mutantes a nivel fenot\u00edpico, gen\u00e9tico y molecular.<\/span><\/strong><\/p>\n

\"l\u00ednea<\/p>\n

Fenotipo vegetativo de mutantes identificados en nuestro laboratorio afectados en genes que codifican prote\u00ednas ribos\u00f3micas cloropl\u00e1sticas (panel superior) o mitocondriales (panel inferior). En la esquina superior izquierda se muestra una foto del silvestre Columbia-0 del que derivan los mutantes.<\/em><\/p>\n

[\/et_pb_tab][et_pb_tab title=”Miembros” _builder_version=”3.0.48″ body_font=”Roboto||||” body_line_height=”2em” tab_font=”Roboto||||” tab_line_height=”2em” background_size=”initial” background_position=”top_left” background_repeat=”repeat” body_line_height_tablet=”2em” body_line_height_phone=”2em” tab_line_height_tablet=”2em” tab_line_height_phone=”2em”]<\/p>\n\n\n\n\n\n
Nombre<\/strong><\/td>\nPuesto<\/strong><\/td>\nCorreo<\/strong><\/td>\nORCID<\/strong><\/td>\n<\/tr>\n
V\u00edctor Manuel Quesada P\u00e9rez<\/td>\nProfesor Titular de Universidad<\/td>\nvquesada@umh.es<\/a><\/td>\n0000-0002-0965-8680<\/td>\n<\/tr>\n
Pedro Robles Ramos<\/td>\nProfesor Titular de Universidad<\/td>\nprobles@umh.es<\/a><\/td>\n0000-0002-4539-5435<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

[\/et_pb_tab][et_pb_tab title=”Publicaciones” _builder_version=”3.0.48″ body_font=”Roboto||||” body_line_height=”2em” tab_font=”Roboto||||” tab_line_height=”2em” background_size=”initial” background_position=”top_left” background_repeat=”repeat” body_line_height_tablet=”2em” body_line_height_phone=”2em” tab_line_height_tablet=”2em” tab_line_height_phone=”2em”]<\/p>\n

P. Robles, V. Quesada
\nResearch Progress in the Molecular Functions of Plant mTERF Proteins<\/a><\/strong>
\nCells 10, 205 (2021).<\/p>\n

E. N\u00fa\u00f1ez-Delegido, P. Robles, A. Ferr\u00e1ndez-Ayela, V. Quesada
\nFunctional analysis of mTERF5 and mTERF9 contribution to salt tolerance, plastid gene expression and retrograde signalling in Arabidopsis thaliana<\/strong><\/a>
\nPlant Biology, 22, 459-471 (2020).<\/p>\n

A. Lid\u00f3n-Soto, E. N\u00fa\u00f1ez-Delegido, I. Pastor-Mart\u00ednez, P. Robles, V.Quesada
\nArabidopsis plastid-RNA polymerase RPOTp is involved in abiotic stress tolerance<\/strong><\/a>
\nPlants 9, 834 (2020).<\/p>\n

P. Robles P, V. Quesada
\nTranscriptional and post-transcriptional regulation of OGE and its roles in plant salt tolerance.<\/strong><\/a>
\nInternational Journal of Molecular Sciences, 20, 1056 (2019).<\/p>\n

P. Robles, E. N\u00fa\u00f1ez-Delegido, A. Ferr\u00e1ndez-Ayela, R. Sarmiento-Ma\u00f1\u00fas, J.L. Micol, V. Quesada
\nArabidopsis mTERF6 is required for leaf patterning.<\/strong><\/a>
\nPlant Science 266, 117-129 (2018).<\/p>\n

P. Robles, V. Quesada
\nOrganelle Genetics in Plants.<\/a><\/strong>
\nInternational Journal of Molecular Sciences 22, 2104 (2021).<\/p>\n

P. Robles, V. Quesada
\nEmerging Roles of Mitochondrial Ribosomal Proteins in Plant Development.<\/a><\/strong>
\nInternational Journal of Molecular Sciences, 18: 2595 (2017).<\/p>\n

V. Quesada
\nThe roles of mitochondrial transcription termination factors (MTERFs) in plants.<\/a><\/strong>
\nPhysiologia Plantarum, 157, 389-399 (2016).<\/p>\n

P. Robles, J.L. Micol, V. Quesada
\nMutations in the plant-conserved MTERF9 alter chloroplast gene expression, development and tolerance to abiotic stress in Arabidopsis thaliana.<\/a><\/strong>
\nPhysiologia Plantarum 154, 297-313 (2015).<\/p>\n

P. Robles, J.L. Micol, V. Quesada
\nArabidopsis MDA1, a nuclear-encoded protein, functions in chloroplast development and abiotic stress responses.<\/a><\/strong>
\nPLoS ONE 8, e42924 (2012).[\/et_pb_tab][et_pb_tab title=”Proyectos” _builder_version=”3.0.48″ body_font=”||||” body_line_height=”2em” tab_font=”||||” tab_line_height=”2em” background_size=”initial” background_position=”top_left” background_repeat=”repeat” body_line_height_tablet=”2em” body_line_height_phone=”2em” tab_line_height_tablet=”2em” tab_line_height_phone=”2em”]<\/p>\n

Caracterizaci\u00f3n gen\u00e9tica y molecular de mutantes afectados en prote\u00ednas ribos\u00f3micas mitocondriales de Arabidopsis thaliana. Funding agency: Universidad Miguel Hern\u00e1ndez de Elche. Duration: desde: 2020 – 2021.
\nPI: V\u00edctor Manuel Quesada P\u00e9rez.<\/em><\/p>\n

\n

Unidad de Microscop\u00eda de Fluorescencia de Hoja de Luz (IDIFEDER\/2018\/016). Instituto de Bioingenier\u00eda. Universidad Miguel Hern\u00e1ndez. Funding agency: Convocatoria de subvenciones para infraestructuras y equipamiento I+D+i de la Generalitat Valenciana. Duration: 2018 – 2020.
\nPI: Jos\u00e9 Manuel P\u00e9rez.<\/em><\/p>\n

\n

Regulaci\u00f3n y nuevas funciones del gen ARGONAUTE1 de Arabidopsis\u201d. Instituto de Bioingenier\u00eda. Universidad Miguel Hern\u00e1ndez. Funding agency: Ministerio de Econom\u00eda y Competitividad. Duration: desde: 2015 – 2017.
\nPI: Mar\u00eda Rosa Ponce.<\/em><\/p>\n

\n

Caracterizaci\u00f3n funcional de los genes mTERF MDA1 y MDA2 de Arabidopsis thaliana\u201d. Instituto de Bioingenier\u00eda. Universidad Miguel Hern\u00e1ndez. Funding agency: Ayudas de la Generalitat Valenciana para grupos de investigaci\u00f3n consolidables. Duration: 2015 – 2016.
\nPI: V\u00edctor Manuel Quesada P\u00e9rez.<\/em><\/p>\n

\n

An\u00e1lisis de la familia g\u00e9nica de los factores de transcripci\u00f3n mTERF en las plantas. Funding agency: Generalitat Valenciana. Duration: 2009 – 2010.
\nPI: V\u00edctor Manuel Quesada P\u00e9rez.<\/em>[\/et_pb_tab][\/et_pb_tabs][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ fullwidth=”on” disabled_on=”off|off|off” admin_label=”Secci\u00f3n” _builder_version=”3.22″][et_pb_fullwidth_header title=”Group of V\u00edctor Quesada and Pedro Robles” text_orientation=”center” content_max_width=”none” admin_label=”T\u00edtulo de anchura completa” _builder_version=”3.16″ background_color=”#649922″ button_one_letter_spacing_hover=”0″ button_two_letter_spacing_hover=”0″ button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”on” button_one_letter_spacing__hover=”0″ button_two_letter_spacing__hover_enabled=”on” button_two_letter_spacing__hover=”0″ button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”off|off|off” admin_label=”section” _builder_version=”3.22″][et_pb_row padding_mobile=”off” column_padding_mobile=”on” admin_label=”row” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” max_width=”980px” make_fullwidth=”off” use_custom_width=”on” width_unit=”on” custom_width_px=”980px”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_tabs admin_label=”Pesta\u00f1as” _builder_version=”4.2.2″ tab_font=”Roboto||||” tab_line_height=”1.4em” background_size=”initial” background_position=”top_left” background_repeat=”repeat” hover_enabled=”0″ use_border_color=”off” border_color=”#ffffff” border_style=”solid”][et_pb_tab title=”Information” _builder_version=”4.2.2″ body_font=”||||” body_line_height=”2em” tab_font=”||||” tab_line_height=”2em” background_size=”initial” background_position=”top_left” background_repeat=”repeat” hover_enabled=”0″ body_line_height_tablet=”2em” body_line_height_phone=”2em” tab_line_height_tablet=”2em” tab_line_height_phone=”2em”]<\/p>\n\n\n\n
Responsible<\/strong><\/td>\nV\u00edctor Quesada y Pedro Robles<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

RESEARCH SUMMARY<\/strong><\/h4>\n

We are performing in our laboratories a reverse genetic approach to identify and characterize Arabidopsis thaliana mutants affected in nuclear genes coding for proteins involved in the flow of genetic information in chloroplasts and mitochondria. For most of the studied genes, there have not been hitherto described any mutant phenotype resulting from impaired function. We are focused in two protein families: the mitochondrial transcription termination factors (mTERFs), and the chloroplast and mitochondrial ribosomal proteins (respectively cpRPs and mtRPs). Our main goal is to shed light on the understanding of the functions of mTERFs, cpRPs and MRPs in plant growth, development and adaptation to abiotic stress, especially to salinity.\u00a0<\/p>\n

RESEARCH LINES<\/strong><\/h4>\n

\n

Line 1:\u00a0Genetic and molecular characterization of the Arabidopsis thaliana<\/i> mitochondrial transcription termination factors (mTERFs)<\/strong><\/h4>\n

The mTERF factors are coded by nuclear genes and in plants they carry out their functions in chloroplasts and mitochondria, where they are required for appropriate organellar gene expression. Land plant genomes include a much higher numbers of mTERF genes than animals. However, only a few of them have been molecularly characterized through the analysis of loss-of-function mutants. We are performing in our laboratories a phenotypic, genetic and molecular characterization of several Arabidopsis mterf mutants (e.g., mda1\/mterf5, mterf6 and mterf9) which show different perturbations in growth and development, as well as an altered response to abiotic stress.<\/p>\n

\"l\u00ednea<\/p>\n

The mterf6 mutants (in red) are more sensitive to salinity stress (150 mM NaCl) than the wild-type Columbia-0 (Col-0; in blue) during germination and seedling establishment (a-d panels). Additionally, the mterf6-5 mutant shows growth, vegetative and reproductive developmental alterations (A-G panels on the right).<\/i><\/p>\n

 <\/p>\n

Line 2:\u00a0Functional analysis of chloroplast and mitochondrial ribosomal proteins in Arabidopsis thaliana<\/i><\/strong><\/h4>\n

Ribosomes, made of RNAs and proteins, are the molecular machinery that translate messenger RNAs in prokaryotes as well as and in the cytoplasm, chloroplasts and mitochondria of eukaryotic cells. With the aim of increasing the understanding of the functions of chloroplast and mitochondrial ribosomal proteins (respectively cpRPs and MRPs) in plants, we have initiated a reverse genetic approach to identify and characterize mutants affected in this kind of proteins in the plant model system Arabidopsis thaliana. We have identified mutant alleles carrying a T-DNA insertion in nuclear genes coding cpRPs or MRPs for which any loss-of-function viable alleles have been hitherto described. Currently we are characterizing these mutant at the phenotypic, genetic and molecular levels.<\/p>\n

\"l\u00ednea<\/p>\n

Rosette phenotypes of mutants affected in nuclear genes encoding chloroplast (upper panel) or mitochondrial (lower panel) ribosomal proteins. In the upper left corner it is shown a picture of the wild-type Columbia-0, the genetic background of all these mutants.<\/i><\/p>\n

[\/et_pb_tab][et_pb_tab title=”Members” _builder_version=”3.0.48″ body_font=”Roboto||||” body_line_height=”2em” tab_font=”Roboto||||” tab_line_height=”2em” background_size=”initial” background_position=”top_left” background_repeat=”repeat” body_line_height_tablet=”2em” body_line_height_phone=”2em” tab_line_height_tablet=”2em” tab_line_height_phone=”2em”]<\/p>\n\n\n\n\n\n
Name<\/strong><\/td>\nPosition<\/strong><\/td>\ne-mail<\/strong><\/td>\nORCID<\/strong><\/td>\n<\/tr>\n
V\u00edctor Manuel Quesada P\u00e9rez<\/td>\nAssociate Professor<\/td>\nvquesada@umh.es<\/a><\/td>\n0000-0002-0965-8680<\/td>\n<\/tr>\n
Pedro Robles Ramos<\/td>\nAssociate Professor<\/td>\nprobles@umh.es<\/a><\/td>\n0000-0002-4539-5435<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

[\/et_pb_tab][et_pb_tab title=”Publications” _builder_version=”4.2.2″ body_font=”Roboto||||” body_line_height=”2em” tab_font=”Roboto||||” tab_line_height=”2em” background_size=”initial” background_position=”top_left” background_repeat=”repeat” hover_enabled=”0″ body_line_height_tablet=”2em” body_line_height_phone=”2em” tab_line_height_tablet=”2em” tab_line_height_phone=”2em”]<\/p>\n

P. Robles, V. Quesada<\/p>\n

Research Progress in the Molecular Functions of Plant mTERF Proteins<\/a><\/strong><\/p>\n

Cells 10, 205 (2021).<\/p>\n

E. N\u00fa\u00f1ez-Delegido, P. Robles, A. Ferr\u00e1ndez-Ayela, V. Quesada<\/p>\n

Functional analysis of mTERF5 and mTERF9 contribution to salt tolerance, plastid gene expression and retrograde signalling in Arabidopsis thaliana<\/strong><\/a><\/p>\n

Plant Biology, 22, 459-471 (2020).<\/p>\n

A. Lid\u00f3n-Soto, E. N\u00fa\u00f1ez-Delegido, I. Pastor-Mart\u00ednez, P. Robles, V.Quesada<\/p>\n

Arabidopsis plastid-RNA polymerase RPOTp is involved in abiotic stress tolerance<\/strong><\/a><\/p>\n

Plants 9, 834 (2020).<\/p>\n

P. Robles P, V. Quesada<\/p>\n

Transcriptional and post-transcriptional regulation of OGE and its roles in plant salt tolerance.<\/strong><\/a><\/p>\n

International Journal of Molecular Sciences, 20, 1056 (2019).<\/p>\n

P. Robles, E. N\u00fa\u00f1ez-Delegido, A. Ferr\u00e1ndez-Ayela, R. Sarmiento-Ma\u00f1\u00fas, J.L. Micol, V. Quesada<\/p>\n

Arabidopsis mTERF6 is required for leaf patterning.<\/strong><\/a><\/p>\n

Plant Science 266, 117-129 (2018).<\/p>\n

P. Robles, V. Quesada<\/p>\n

Organelle Genetics in Plants.<\/a><\/strong><\/p>\n

International Journal of Molecular Sciences 22, 2104 (2021).<\/p>\n

P. Robles, V. Quesada<\/p>\n

Emerging Roles of Mitochondrial Ribosomal Proteins in Plant Development.<\/a><\/strong><\/p>\n

International Journal of Molecular Sciences, 18: 2595 (2017).<\/p>\n

V. Quesada<\/p>\n

The roles of mitochondrial transcription termination factors (MTERFs) in plants.<\/a><\/strong><\/p>\n

Physiologia Plantarum, 157, 389-399 (2016).<\/p>\n

P. Robles, J.L. Micol, V. Quesada<\/p>\n

Mutations in the plant-conserved MTERF9 alter chloroplast gene expression, development and tolerance to abiotic stress in Arabidopsis thaliana.<\/a><\/strong><\/p>\n

Physiologia Plantarum 154, 297-313 (2015).<\/p>\n

P. Robles, J.L. Micol, V. Quesada<\/p>\n

Arabidopsis MDA1, a nuclear-encoded protein, functions in chloroplast development and abiotic stress responses.<\/a><\/strong><\/p>\n

PLoS ONE 8, e42924 (2012).<\/p>\n

[\/et_pb_tab][et_pb_tab title=”Projects” _builder_version=”3.0.48″ body_font=”||||” body_line_height=”2em” tab_font=”||||” tab_line_height=”2em” background_size=”initial” background_position=”top_left” background_repeat=”repeat” body_line_height_tablet=”2em” body_line_height_phone=”2em” tab_line_height_tablet=”2em” tab_line_height_phone=”2em”]<\/p>\n

Caracterizaci\u00f3n gen\u00e9tica y molecular de mutantes afectados en prote\u00ednas ribos\u00f3micas mitocondriales de Arabidopsis thaliana. Agencia de financiaci\u00f3n: Universidad Miguel Hern\u00e1ndez de Elche. Vigencia: desde: 2020 – 2021.<\/p>\n

PI: V\u00edctor Manuel Quesada P\u00e9rez.<\/em><\/p>\n

\n

Unidad de Microscop\u00eda de Fluorescencia de Hoja de Luz (IDIFEDER\/2018\/016). Instituto de Bioingenier\u00eda. Universidad Miguel Hern\u00e1ndez. Agencia de financiaci\u00f3n: Convocatoria de subvenciones para infraestructuras y equipamiento I+D+i de la Generalitat Valenciana. Vigencia: 2018 – 2020.<\/p>\n

PI: Jos\u00e9 Manuel P\u00e9rez.<\/em><\/p>\n

\n

Regulaci\u00f3n y nuevas funciones del gen ARGONAUTE1 de Arabidopsis\u201d. Instituto de Bioingenier\u00eda. Universidad Miguel Hern\u00e1ndez. Agencia de financiaci\u00f3n: Ministerio de Econom\u00eda y Competitividad. Vigencia: desde: 2015 – 2017.<\/p>\n

PI: Mar\u00eda Rosa Ponce.<\/em><\/p>\n

\n

Caracterizaci\u00f3n funcional de los genes mTERF MDA1 y MDA2 de Arabidopsis thaliana\u201d. Instituto de Bioingenier\u00eda. Universidad Miguel Hern\u00e1ndez. Agencia de financiaci\u00f3n: Ayudas de la Generalitat Valenciana para grupos de investigaci\u00f3n consolidables. Vigencia: 2015 – 2016.<\/p>\n

PI: V\u00edctor Manuel Quesada P\u00e9rez.<\/em><\/p>\n

\n

An\u00e1lisis de la familia g\u00e9nica de los factores de transcripci\u00f3n mTERF en las plantas. Agencia de financiaci\u00f3n: Generalitat Valenciana. Vigencia: 2009 – 2010.<\/p>\n

PI: V\u00edctor Manuel Quesada P\u00e9rez.<\/em><\/p>\n

[\/et_pb_tab][\/et_pb_tabs][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”on|on|on” _builder_version=”4.2.2″ disabled=”on”][et_pb_row _builder_version=”4.2.2″][et_pb_column type=”4_4″ _builder_version=”4.2.2″][:es _i=”0″ _address=”4.0.0.0″ \/][:en _i=”1″ _address=”4.0.0.1″ \/][: _i=”2″ _address=”4.0.0.2″ \/][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"

Responsable V\u00edctor Quesada y Pedro Robles   RESUMEN DE LA INVESTIGACI\u00d3N En nuestros laboratorios se lleva a cabo una aproximaci\u00f3n de gen\u00e9tica inversa con el fin de identificar y caracterizar en Arabidopsis thaliana, mutantes afectados en genes nucleares que codifican prote\u00ednas implicadas en el flujo de la informaci\u00f3n gen\u00e9tica en los cloroplastos y las mitocondrias. […]<\/p>\n","protected":false},"author":17017,"featured_media":0,"parent":4240,"menu_order":50,"comment_status":"open","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_links_to":"","_links_to_target":""},"_links":{"self":[{"href":"https:\/\/bioingenieria.umh.es\/en\/wp-json\/wp\/v2\/pages\/4462"}],"collection":[{"href":"https:\/\/bioingenieria.umh.es\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/bioingenieria.umh.es\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/bioingenieria.umh.es\/en\/wp-json\/wp\/v2\/users\/17017"}],"replies":[{"embeddable":true,"href":"https:\/\/bioingenieria.umh.es\/en\/wp-json\/wp\/v2\/comments?post=4462"}],"version-history":[{"count":0,"href":"https:\/\/bioingenieria.umh.es\/en\/wp-json\/wp\/v2\/pages\/4462\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/bioingenieria.umh.es\/en\/wp-json\/wp\/v2\/pages\/4240"}],"wp:attachment":[{"href":"https:\/\/bioingenieria.umh.es\/en\/wp-json\/wp\/v2\/media?parent=4462"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}