- Seminar
- Dr. Agata Jabłońska Trypuć
- Organizers: IB
- April 18, 2024, 12:00 h.
- Assembly hall of the Institute of Bioengineering Vinalopó building.
Brief description of the talk
The scientific literature describes a robust relationship between exposure to various types of pesticides and the development of chronic diseases, including cancer. The induction of oxidative stress is one of the mechanisms of pesticide toxicity that would be related to such adverse effects. However, many bioactive substances of plant origin have recently been recognized as chemopreventive substances due to their ability to neutralize free radicals generated by pesticides. Such phytochemical compounds must scavenge free radicals, as well as be easily absorbed and function at an adequate physiological level. Their main function is to maintain the redox balance and minimize cell damage caused by ROS, so they must be active in aqueous solutions and/or lipid environments. These properties are fulfilled in phenolic compounds and plant hormones selected for their antioxidant activity with which the negative effects of pesticides could be neutralized, at least in part.”
Other information of interest
Dr. Agata Jabłońska-Trypuć (Bialystok University of Technology, Faculty of Civil Engineering and Environmental Sciences, Department of Chemistry, Biology and Biotechnology, Poland) focuses her research in the field of Environmental and Biomedical Engineering and has published 46 papers. Dr. Agata Jabłońska-Trypuć She is a principal investigator of a research group funded by the Polish Ministry of Science and Higher Education with the aim of developing methods for toxicity testing of xenobiotics present in the environment in various biological models (W/WB-IIŚ/6/2022). He has also evaluated the estrogenic potential of various environmental pollutants for their endocrine disrupting properties (G/WB-IIŚ/2/2021). The main results of her publications are the characterization of the toxicological profile of selected herbicides analyzed using cancer cell lines, the description of molecular mechanisms of herbicide action at the cellular level, as well as the determination of their impact on carcinogenic potential and ecotoxicity in bacteria and fungi. Dr. Agata is a member of the Polish Federation of Biotechnology, the Polish Society of Cell Biology and the Scientific Council of the Research and Science Innovation Center in Lublin (Poland).