TOXICOLOGY UNIT

GROUPS

The Toxicology and Chemical Safety Unit of the Institute of Bioengineering of the Miguel Hernández University is formed by the following research groups:

Toxicology and Environmental Health

The group is focused on the study of molecular mechanisms of toxicity and identification of adverse effect pathways of various xenobiotics, from nanoparticles to organophosphorus compounds such as pesticides, flame retardants. The group is also active in regulatory toxicology and in the preparation of risk assessment reports on exposure to various chemicals for human health and the environment.

Toxicology and Population Risk

The main objective of the research group is to study the mechanisms of toxicity and modifying factors, both genetic and environmental, that affect the response of populations exposed to environmental pollutants, such as persistent organic compounds and endocrine disruptors, drugs and addictive substances.

Clinical Pharmacology

In the Clinical Pharmacology group we investigate interindividual variability in drug response, especially in the area of pain and cognitive diversity. Our work focuses on the monitoring of adverse events and the use of pharmacogenetic markers to improve the benefit/risk of drugs. To this end, we have specific lines of work on drugs abuse and dependence, as well as sleep disorders. The analysis of sex/gender interaction is included as a cross-cutting theme in all of them.